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Article

Replication of associations between LRP5 and ESRRA variants and bone density in premenopausal women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Dec 2008

Giroux S, Elfassihi L, Cole D E C, Rousseau F

Abstract excerpt

UNLABELLED: Replication is a critical step to validate positive genetic associations. In this study, we tested two previously reported positive associations. The low density lipoprotein receptor-related protein 5 (LRP5) Val667Met and lumbar spine bone density are replicated. This result is in line with results from large consortiums such as Genomos. However, the estrogen-related receptor alpha (ESRRA) repeat in...

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Source

Identifiers

PMID: 18418639
DOI: 10.1007/s00198-008-0617-z

Genes

ESRRA
LRP5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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