Article
Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
Gallego Patricia H, Shephard Neil, Bulsara Max K, van Bockxmeer Frank M, Powell Brenda L, Beilby John P, Arscott Gillian, Le Page Michael, Palmer Lyle J, Davis Elizabeth A, Jones Timothy W, Choong Catherine S Y
Abstract excerpt
AIM: We examined genetic polymorphisms in the renin-angiotensin system (RAS) coding for angiotensin I-converting enzyme (ACE) insertion/deletion (I/D) for angiotensinogen (AGT) M235T and angiotensin II receptor type 1 (AGTR1) A1166C as predictors for the development of microalbuminuria (MA) in children with type 1 diabetes mellitus (T1DM). METHODS: Four hundred fifty-three (215 males, 238 females) T1DM children...
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