Article
Association of the -250G/A promoter polymorphism of the hepatic lipase gene with the risk of peripheral arterial disease in type 2 diabetic patients.
Journal of diabetes and its complications - 1 Jan 2000
Valdivielso Pedro, Ariza María José, de la Vega-Román Cristobal, González-Alegre Teresa, Rioja José, Ulzurrun Eugenia, González-Santos Pedro
Abstract excerpt
AIM: This study aimed to investigate the association between a polymorphism in the hepatic lipase (LIPC) gene promoter and the presence of peripheral arterial disease (PAD) in persons with type 2 diabetes. PATIENT AND METHODS: We evaluated 120 type 2 diabetics and identified those with PAD according to the ankle-arm index. The G-250A polymorphisms in the promoter of the LIPC gene were studied by PCR restriction....
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