Article
Mutation analyses of integrated HBV genome in hepatitis B patients.
Journal of genetics and genomics = Yi chuan xue bao - 1 Feb 2008
Wang Peilin, Wang Xiuhai, Cong Shuying, Ma Hongming, Zhang Xuecheng
Abstract excerpt
Little has been learnt in the last 30 years about detection of HBV genome as well as its mutation analysis between hepatitis B fathers (HBF) and their children. In this study, we used nest polymerase chain reaction (PCR), fluorescence in situ hybridization (FISH), and DNA sequencing analysis, to examine the integrated HBV genome in paraffin-embedded testis tissues, which were taken as samples from HBF, and in...
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