Article
In vivo and in vitro studies of GAD-antibody positive subjects with Type 2 diabetes: A distinct sub-phenotype.
Diabetes research and clinical practice - 1 Jun 2008
O'Gorman Donal J, Yousif Obada, Dixon Gordon, McQuaid Siobhan, Murphy Elaine, Rahman Yousif, Gasparro Declan, Pacini Giovanni, Newsholme Philip, Nolan John J
Abstract excerpt
The purpose of this study was to determine if immune mechanisms in GAD positive patients' contribute to the pathogenesis of a specific sub-type of Type 2 diabetes. GAD positive (n=8) and GAD negative (n=8) subjects diagnosed with Type 2 diabetes were matched for age, gender, body mass index, duration of diabetes and glycaemic control. All subjects underwent an insulin-modified frequently sampled intravenous...
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