Article
Developments in the prediction of type 1 diabetes mellitus, with special reference to insulin autoantibodies.
Diabetes/metabolism research and reviews - 1 Jan 2000
Franke Bernd, Galloway Tamara S, Wilkin Terry J
Abstract excerpt
The prodromal phase of type 1 diabetes is characterised by the appearance of multiple islet-cell related autoantibodies (Aab). The major target antigens are islet-cell antigen, glutamic acid decarboxylase (GAD), protein-tyrosine phosphatase-2 (IA-2) and insulin. Insulin autoantibodies (IAA), in contrast to the other autoimmune markers, are the only beta-cell specific antibodies. There is general consensus that...
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