Article
Occurrence of cancer at multiple sites: towards distinguishing multigenesis from metastasis.
Biology direct - 11 Apr 2008
Zhang Wei-Kang, Zhang Chun, Zhang Jing J, Liu Shi V
Abstract excerpt
BACKGROUND: Occurrence of tumors at multiple sites is a hallmark of malignant cancers and contributes to the high mortality of cancers. The formation of multi-site cancers (MSCs) has conventionally been regarded as a result of hematogenous metastasis. However, some MSCs may appear as unusual in the sense of vascular dissemination pattern and therefore be explained by alternative metastasis models or even by...
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