Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of the H3O+-Lys-164 -Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H+,K+-ATPase.

The Journal of biological chemistry - 13 Jun 2008

Morii Magotoshi, Yamauchi Masashi, Ichikawa Tomohiko, Fujii Takuto, Takahashi Yuji, Asano Shinji, Takeguchi Noriaki, Sakai Hideki

Abstract excerpt

Gastric H(+),K(+)-ATPase is shown to transport 2 mol of H(+)/mol of ATP hydrolysis in isolated hog gastric vesicles. We studied whether the H(+) transport mechanism is due to charge transfer and/or transfer of hydronium ion (H(3)O(+)). From transport of [(18)O]H(2)O, 1.8 mol of water molecule/mol...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Biological Transport
Share to Cytosol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastric Mucosa

Share to Hydrolysis

Share to Mutagenesis, Site-Directed

Share to Protons

Source

Identifiers

PMID: 18403373
DOI: 10.1074/jbc.M800563200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18403373-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of the H3O+-Lys-164 -Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H+,K+-ATPase.PMID 18403373Read ↗

Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations.Semantic proximity Read ↗

A conformation-specific interhelical salt bridge in the K+ binding site of gastric H,K-ATPase.Semantic proximity Read ↗

Catalytic site in the beta subunit of H(+)-ATPase from Escherichia coli:the glycine-rich sequence and its interaction with Ser-174.Semantic proximity Read ↗

Deceleration of the E1P-E2P transition and ion transport by mutation of potentially salt bridge-forming residues Lys-791 and Glu-820 in gastric H+/K+-ATPase.Semantic proximity Read ↗

Proton transport pathway in the ClC Cl-/H+ antiporter.Semantic proximity Read ↗

The role of protons in fast and slow gating of the Torpedo chloride channel ClC-0.Semantic proximity Read ↗

Inhibitor and ion binding sites on the gastric H,K-ATPase.Semantic proximity Read ↗

Asn792 participates in the hydrogen bond network around the K+-binding pocket of gastric H,K-ATPase.Semantic proximity Read ↗

Selectivity Mechanism of the Voltage-gated Proton Channel, HV1.Semantic proximity Read ↗

Functional transfer of an essential aspartate for the ion-binding site in the stator proteins of the bacterial flagellar motor.Semantic proximity Read ↗

"Proton holes" in long-range proton transfer reactions in solution and enzymes: A theoretical analysis.Semantic proximity Read ↗

Role of conserved TGDGVND-loop in Mg2+ binding, phosphorylation, and energy transfer in Na,K-ATPase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.