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Article

An evolutionary perspective on Y‐chromosomal variation and male infertility

9 Apr 2008

Abstract excerpt

Genetic variation on the Y chromosome is one of the best-documented causes of male infertility, but the genes responsible have still not been identified. This review discusses how an evolutionary perspective may help with interpretation of the data available and suggest novel approaches to identify key genes. Comparison with the chimpanzee Y chromosome indicates that USP9Y is dispensable in apes, but that...

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PMID: 18399979
DOI: 10.1111/j.1365-2605.2008.00889.x

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