Article
SNP detection for cytochrome P450 alleles by target-assembled tandem oligonucleotide systems based on exciplexes.
Journal of biomolecular structure & dynamics - 1 Jun 2008
Walsh Lindsey, Gbaj Abdul, Etchells Laura L, Douglas Kenneth T, Bichenkova Elena V
Abstract excerpt
We report the first use of exciplex-based split-probes for detection of the wild type and *3 mutant alleles of human cytochrome P450 2C9. A tandem 8-mer split DNA oligonucleotide probe system was designed that allows detection of the complementary target DNA sequence. This exciplex-based fluoresc...
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