Article
Chloroquine prophylaxis associated with high prevalence of Plasmodium falciparum pfcrt K76T mutation in people with sickle-cell disease in Benin City, Nigeria.
Journal of vector borne diseases - 1 Mar 2008
Tatfeng Y M, Agbonlahor D E, Tchounga K S, Omolu P I, Okodua M, Yah C S, Adeolu A
Abstract excerpt
BACKGROUND & OBJECTIVES: High mortality and morbidity in sickle-cell disease has been associated with malaria infection especially in countries where chloroquine is used. Chloroquine resistance has been associated with the emergence of Pfcrt mutant genes. This study aimed at comparing the prevale...
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