Article
Single nucleotide polymorphisms in obesity-related genes and the risk of esophageal cancers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2008
Doecke James D, Zhao Zhen Zhen, Stark Mitchell S, Green Adèle C, Hayward Nicholas K, Montgomery Grant W, Webb Penelope M, Whiteman David C
Abstract excerpt
Rates of adenocarcinoma of the esophagus (EAC) and esophagogastric junction (EGJAC) have been rising rapidly in recent decades, in contrast to the declining rates of esophageal squamous cell carcinomas (ESCC). Obesity is a major risk factor for both EAC and EGJAC, but not ESCC, and there is speculation that obesity promotes adenocarcinoma development through endocrine and related pathways. We therefore compared...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.