Article
Interleukin 8 and susceptibility to coronary artery disease: a population genetics perspective.
Journal of clinical immunology - 1 Jul 2008
Vogiatzi Konstantina, Apostolakis Stavros, Voudris Vassilios, Thomopoulou Sophia, Kochiadakis Georgios E, Spandidos Demetrios A
Abstract excerpt
INTRODUCTION: Interleukin 8 is a strong chemoattractant factor for neutrophils and T lymphocytes. We investigated the potential influence of two common polymorphisms of the interleukin-8 gene, -251A/T, and 781C/T on susceptibility to coronary artery disease. MATERIALS AND METHODS: The hypothesis was tested by screening for the prevalence of the above polymorphisms in 241 angiographically diagnosed coronary artery...
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