Article
Heritability of IL-1A Gene Promoter Polymorphism in Patients With Coronary Artery Disease: A Trio-Family Study.
Laboratory medicine - 1 Jan 2015
Haroon Javeria, Hussain Sabir, Javed Qamar
Abstract excerpt
OBJECTIVE: To investigate the potential role of IL-1A gene variations in pathogenesis of coronary artery disease (CAD) with familial history. MATERIALS AND METHODS: We investigated the IL-1A-889C>T polymorphism in 335 patients with CAD and 335 healthy individuals for case-control association analysis. In this study, we also investigated the heritability of the susceptible allele from 130 trio families with...
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