Article
Radiation-induced glioblastoma in a medulloblastoma patient: a case report with molecular features.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Dec 2008
Gessi Marco, Maderna Emanuela, Guzzetti Sara, Cefalo Graziella, Massimino Maura, Solero Carlo L, Finocchiaro Gaetano, Pollo Bianca
Abstract excerpt
We report a case of glioblastoma (GBM) occurring 8 years after radiation therapy for a medulloblastoma. A 15-year-old boy underwent surgery and radiotherapy for a medulloblastoma and 8 years later he developed a second tumor at the same site. The second lesion showed different histological and molecular features, was diagnosed as a glioblastoma and fulfilled the criteria of radiation-induced neoplasm. Mutational...
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