Article
Worse prognosis with gene mutations of beta-myosin heavy chain than myosin-binding protein C in Chinese patients with hypertrophic cardiomyopathy.
Clinical cardiology - 1 Mar 2008
Wang Shuxia, Zou Yubao, Fu Chunyan, Xu Xiqi, Wang Jizheng, Song Lei, Wang Hu, Chen Jingzhou, Wang Jianwei, Huan Tujun, Hui Rutai
Abstract excerpt
BACKGROUND: No data are available on survival analysis and longitudinal evolution of patients with gene mutations of beta-myosin heavy chain (MYH7) and myosin binding protein C (MYBPC3) in Chinese. HYPOTHESIS: To prospectively investigate whether different gene mutations confer distinct prognosis. METHODS: We performed a prospective study in 70 HCM patients and 46 genetically affected family members without...
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