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Article

Mutations profile in Chinese patients with hypertrophic cardiomyopathy.

Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2005

Song Lei, Zou Yubao, Wang Jizheng, Wang Zhimin, Zhen Yisong, Lou Kejia, Zhang Qian, Wang Xiaojian, Wang Hu, Li Jia, Hui Rutai

Abstract excerpt

BACKGROUND: There are more than 1 million patients with hypertrophic cardiomyopathy (HCM) in China, but the genetic basis is presently unknown. METHODS: We investigated 100 independent patients with HCM (proband 51, sporadic 49) by sequencing the three most frequent HCM-causing genes (MYH7, MYBPC3, TNNT2). RESULTS: Thirty-four patients (34%) carried 25 types of mutations in the selected genes, most (14/25) were...

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Source

Identifiers

PMID: 15563892
DOI: 10.1016/j.cccn.2004.09.016

Genes

MYH7
MYBPC3
TNNT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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