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Article

BRCA1 and stem cells: tumour typecasting.

Nature cell biology - 1 Apr 2008

Smalley Matthew J, Reis-Filho Jorge S, Ashworth Alan

Abstract excerpt

Phenotypic variation between tumour types is likely to reflect the nature of the cell of origin and the genes involved in pathogenesis. Compared with most sporadic breast cancers, those arising in carriers of BRCA1 mutations usually have distinctive pathological characteristics. A new study sugge...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 18379596
DOI: 10.1038/ncb0408-377

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18379596-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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