Article
Cancer, stem cell misplacement and cancer stem cells.
Journal of cellular and molecular medicine - 1 Sept 2013
Liao Yong
Abstract excerpt
The cell of origin of cancer as well as cancer stem cells is still a mystery. In a recent issue of JCMM, Wang et al. challenged the conventional somatic genetic mutation model of multi-stage carcinogenesis of breast cancer and proposed that 'Invasive cancers are not necessary from preformed in situ tumours-an alternative way of carcinogenesis from misplaced stem cells'. If this stem cell misplacement theory could...
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