Article
Endothelial nitric oxide synthase polymorphisms associated with abnormal nitric oxide production are not over-represented in children with Down syndrome.
Congenital heart disease - 1 Jul 2006
Cua Clifford L, Cooke Glen, Taylor Mackenzie, Hayes John, Waldon Laurie, Lipowski Patricia, Kossman Beth, Nash Patricia L
Abstract excerpt
OBJECTIVE: Down syndrome patients are at increased risk for developing pulmonary hypertension (PHTN). Nitric oxide (NO) is an important factor for pulmonary vasoreactivity. Various endothelial nitric oxide synthase (eNOS) polymorphisms have been shown to affect NO. The goal of this study was to determine whether there was a difference in prevalence of eNOS polymorphisms between Down syndrome patients vs. non-Down...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.