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Article

Expression of cancer testis antigens in human BRCA-associated breast cancers: potential targets for immunoprevention?

Cancer immunology, immunotherapy : CII - 1 Jul 2011

Adams Sylvia, Greeder Luba, Reich Elsa, Shao Yongzhao, Fosina Denise, Hanson Nicole, Tassello Jodie, Singh Baljit, Spagnoli Giulio C, Demaria Sandra, Jungbluth Achim A

Abstract excerpt

INTRODUCTION: Novel breast cancer risk-reducing strategies for individuals with germline mutations of the BRCA1 and/or BRCA2 genes are urgently needed. Identification of antigenic targets that are expressed in early cancers, but absent in normal breast epithelium of these high-risk individuals, could provide the basis for the development of effective immunoprophylactic strategies. Cancer testis (CT) antigens are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 21465317
DOI: 10.1007/s00262-011-1005-7
PMCID: PMC3678385

Genes

BRCA1
BRCA2
C2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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