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Article

Regulatory role of cytochrome P450scc and pregnenolone in myelination by rat Schwann cells.

Molecular and cellular biochemistry - 1 Jun 2008

Zhu Thant S, Glaser Michael

Abstract excerpt

To investigate the production of steroid hormones by Schwann cells and to examine the regulation of steroid hormone production during myelination, cultures of rat Schwann cells were differentiated into their myelinating phenotype in the absence of neurons with dibutyryl cAMP (db-cAMP). During this process, the expression of P450scc (involved in steroid biosynthesis) was elevated at both the mRNA and protein...

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Identifiers

PMID: 18373277
DOI: 10.1007/s11010-008-9745-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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