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Article

Evidence that secondary rat Schwann cells in culture maintain their differentiated phenotype.

Journal of neurochemistry - 1 Jun 1990

Rutkowski L, Needham L, Frayer K, Carson D, McKhann G, Tennekoon G I

Abstract excerpt

Schwann cells, on receiving the correct signal, will encircle an axon and wrap it with a myelin sheath. To begin examining some of the mechanisms underlying the process of myelination in vitro, we isolated Schwann cells from the sciatic nerves of neonatal rats and generated large cell populations with cholera toxin. The immunological and biochemical properties of these secondary Schwann cells were characterized...

Topics

Animals
Cell Differentiation
Cell Division
Cells, Cultured
Dolichol Phosphates
Fatty Acids
Fluorescent Antibody Technique
Glycolipids
Myelin Proteins
Oligosaccharides
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Schwann Cells

Staining and Labeling

Source

Identifiers

PMID: 1692582
DOI: 10.1111/j.1471-4159.1990.tb04888.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1692582-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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