Article
Mutants lacking individual ribosomal proteins as a tool to investigate ribosomal properties.
Biochimie - 1 Jun 1991
Dabbs E R
Abstract excerpt
We have isolated and characterized mutants which lack one or two of sixteen of the proteins of the Escherichia coli ribosome. The mutation responsible in each case mapped close to, and probably in, the corresponding gene. A conditional lethal phenotype and a variable degree of impairment in growt...
Topics
- Aminoglycosides
- Anti-Bacterial Agents
- Drug Resistance, Microbial
- Erythromycin
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Macromolecular Substances
- Mutation
- Phenotype
- Ribosomal Proteins
- Ribosomes
- Spectinomycin
