Identification and characterization of interacting partners of Rab GTPases by yeast two-hybrid analyses.

Abstract excerpt

Much of our knowledge of the mechanisms governing vesicular transport has come from the combination of genetic and biochemical approaches that have identified Ypt/Rab guanosine 5'-triphosphatases (GTPases) as key components of transport processes in both yeast and mammalian cells. More recently, research has focused on establishing the complex protein-protein interactions necessary for the regulation of vesicular...

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