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Article

Expression of NANOG, but not POU5F1, points to the stem cell potential of primitive germ cells in neonatal pig testis

11 Apr 2008

Abstract excerpt

Gonocytes are primitive germ cells that are present in the neonatal testis and are committed to male germline development. Gonocytes differentiate to spermatogonia, which establish and maintain spermatogenesis in the postnatal testis. However, it is unknown whether large animal species have pluripotency-specific proteins in the testis. Nanog and Pou5f1 (Oct3/4) have been identified as transcription factors...

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PMID: 18367503
DOI: 10.1530/rep-07-0476

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