Article
Primer: strategies for identifying genes involved in renal disease.
Nature clinical practice. Nephrology - 1 May 2008
de Borst Martin H, Benigni Ariela, Remuzzi Giuseppe
Abstract excerpt
The globally increasing number of patients with end-stage renal disease urges the identification of molecular pathways involved in renal pathophysiology, to serve as targets for intervention. Moreover, the identification of genetic risk factors or protective genes can aid tailored therapy. Tools that can be used to identify genes involved in renal disease include gene expression arrays, linkage analysis and...
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