Article
Family based association study of pediatric bipolar disorder and the dopamine transporter gene (SLC6A3).
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Mick Eric, Kim Jang Woo, Biederman Joseph, Wozniak Janet, Wilens Timothy, Spencer Thomas, Smoller Jordan W, Faraone Stephen V
Abstract excerpt
The dopamine transporter gene (SLC6A3) is a compelling candidate for pediatric bipolar disorder because (a) it has been associated with ADHD, (b) bipolar comorbidity with ADHD has been hypothesized to be an etiologically distinct familial subtype (c) blockade of the dopamine transporter with psychostimulants can induce mania in susceptible individuals and (d) previous studies have implicated the gene in bipolar...
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