Article
GAD1 single nucleotide polymorphism is in linkage disequilibrium with a child bipolar I disorder phenotype.
Journal of child and adolescent psychopharmacology - 1 Feb 2008
Geller Barbara, Tillman Rebecca, Bolhofner Kristine, Hennessy Kathleen, Cook Edwin H
Abstract excerpt
BACKGROUND: Pediatric bipolar I disorder (BP-I) and childhood schizophrenia (SZ) share certain symptoms (e.g., psychosis, aggression/irritability [A/I]), and the psychotic and A/I features are treated with neuroleptics in both disorders. Thus, it is of interest to examine the association of GAD1 to child BP-I because of its recently reported association to childhood SZ. METHODS: Child BP-I probands were obtained...
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