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Article

Prostate cancer: a model of integration of genomic and non-genomic effects of the androgen receptor in cell lines model.

Steroids - 1 Oct 2008

Bonaccorsi Lorella, Nosi Daniele, Quercioli Franco, Formigli Lucia, Zecchi Sandra, Maggi Mario, Forti Gianni, Baldi Elisabetta

Abstract excerpt

Androgens and the androgen receptor (AR) are involved both in early tumorigenesis of prostate cancer (PCa) and in androgen-refractory disease. The role of AR signalling has also been highlighted by the fusion gene TMPRSS2:ERG recently identified in the majority of PCa. Several data indicate that re-expression of AR in PCa cell lines confers a less aggressive phenotype. We observed that re-expression of AR in the...

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Source

Identifiers

PMID: 18358509
DOI: 10.1016/j.steroids.2008.01.028

Genes

EGFR
ERG
TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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