Article
Female oxytocin gene-knockout mice, in a semi-natural environment, display exaggerated aggressive behavior.
Genes, brain, and behavior - 1 Jun 2005
Ragnauth A K, Devidze N, Moy V, Finley K, Goodwillie A, Kow L-M, Muglia L J, Pfaff D W
Abstract excerpt
Compared to results from a generation of neuropharmacological work, the phenotype of mice lacking the oxytocin (OT) peptide gene was remarkably normal. An important component of the current experiments was to assay OT-knockout (OTKO) and wild-type (WT) littermate control mice living under controlled stressful conditions designed to mimic more closely the environment for which the mouse genome evolved....
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