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Article

Notch1, Jagged1, and HES5 Are Abundantly Expressed in Osteoarthritis

1 Jan 2008

Abstract excerpt

BACKGROUND: Notch signalling controls differentiation and proliferation in various cell types and is associated with several diseases. We investigated the localization and regulation of several Notch markers in human osteoarthritic (OA) cartilage as well as identified genes controlled by Notch signalling. METHODS: Immunolocalization and real-time PCR analysis of Notch markers in healthy and OA articular cartilage...

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PMID: 18354251
DOI: 10.1159/000121610

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