Article
Genetic variant in the glucose transporter type 2 is associated with higher intakes of sugars in two distinct populations.
Physiological genomics - 13 May 2008
Eny Karen M, Wolever Thomas M S, Fontaine-Bisson Bénédicte, El-Sohemy Ahmed
Abstract excerpt
Glucose sensing in the brain has been proposed to be involved in regulating food intake, but the mechanism is not known. Glucose transporter type 2 (GLUT2)-null mice fail to control their food intake in response to glucose, suggesting a potential role for this transporter as a glucose sensor in the brain. Here we show that individuals with a genetic variation in GLUT2 (Thr110Ile) have a higher daily intake of...
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