Molecular cloning of estrogen receptors from fathead minnow (Pimephales promelas) and bluegill (Lepomis macrochirus) fish: limited piscine variation in estrogen receptor-mediated reporter gene transactivation by xenoestrogens.

Abstract excerpt

Estrogen receptors (ERs) play essential roles in estrogen function. Because they may be targets of environmental chemicals, concern exists that exposure to some anthropogenic agents may result in disruption of endocrine systems in human and wildlife populations. Various kinds of ERs have been reported, and a number of in vitro assays have been established to test hormone-like activity of chemicals. In the present...

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