Article
Autoimmunity causing thyroid dysfunction.
Endocrinology and metabolism clinics of North America - 1 Sept 1991
Volpé R
Abstract excerpt
Considerable evidence for a genetically induced antigen-specific defect in suppressor T lymphocytes as the basis for AITD has been derived from several laboratories and via different types of experimental techniques. This defect may result from abnormal antigen presentation to T lymphocytes via an aberrant antigen-specific HLA-related gene. In addition, there is now evidence for additive effects on reducing...
Topics
- Antibodies, Anti-Idiotypic
- Autoimmune Diseases
- B-Lymphocytes
- Humans
- Mutation
- T-Lymphocytes
- T-Lymphocytes, Regulatory
- Thyroid Diseases
- Thyroiditis, Autoimmune