Article
Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation.
Journal of the American College of Cardiology - 18 Mar 2008
Darbar Dawood, Hardy Amanda, Haines Jonathan L, Roden Dan M
Abstract excerpt
OBJECTIVES: This study sought to perform a genome-wide linkage analysis in a large atrial fibrillation (AF) kindred using AF and abnormally prolonged signal-averaged (SA) P-wave duration as the phenotype. BACKGROUND: Although inherited forms of AF exist, phenotypic complexity has limited efforts to ascertain mutation carriers and thus identify causal genes. The identification of intermediate or endophenotypes may...
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