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Article

Genetic polymorphisms and human aging: association studies deliver.

Rejuvenation research - 1 Apr 2008

Melzer David

Abstract excerpt

Aging shows great heterogeneity between people, with a substantial part attributable to genetic differences. In a candidate gene study across three older populations, polymorphisms in the p16/p15 locus (INK4a/INK4b, CDKN2a/b) were associated with a substantial difference in levels of physical functioning. Recent large-scale genome wide association (GWA) studies for type 2 diabetes and myocardial infarction have...

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PMID: 18341427
DOI: 10.1089/rej.2008.0684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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