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Article

Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology.

Mechanisms of development - 1 Jan 2000

Oginuma Masayuki, Hirata Tatsumi, Saga Yumiko

Abstract excerpt

Bacterial artificial chromosome (BAC) modification technology is a powerful method for the identification of enhancer sequences and genetic modifications. Using this method, we have analyzed the Mesp1 and/or Mesp2 enhancers and identified P1-PSME, a PSM-specific enhancer of Mesp1, which contains...

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Share to Basic Helix-Loop-Helix Transcription Factors
Share to Chromosomes, Artificial, Bacterial
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Mesoderm

Share to Mice, Knockout

Share to Recombination, Genetic

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 18328678
DOI: 10.1016/j.mod.2008.01.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18328678-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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