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Article

High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma

6 Mar 2008

Abstract excerpt

BACKGROUND: The prognosis of adenoid cystic carcinoma (ACC), a malignant salivary gland tumour, depends on clinicopathological parameters. To decipher the biological behaviour of ACC, and to identify patients at risk of developing metastases, additional markers are needed. METHODS: Expression of the cell cycle proteins p53, cyclin D1, p16(INK4a), E2F1 and Ki-67, together with the Polycomb group (PcG) proteins...

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PMID: 18326020
DOI: 10.1136/jcp.2007.054262

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