Is the interleukin-6 haplotype a prognostic factor for sciatica?

doi:10.1016/j.ejpain.2008.01.009

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Article

Is the interleukin-6 haplotype a prognostic factor for sciatica?

European journal of pain (London, England) - 1 Nov 2008

Karppinen Jaro, Daavittila Iita, Noponen Noora, Haapea Marianne, Taimela Simo, Vanharanta Heikki, Ala-Kokko Leena, Männikkö Minna

Abstract excerpt

AIMS: We have shown in a cross-sectional setting that an IL6 haplotype (GGGA) is associated with intervertebral disc disease (IDD) characterized by sciatica. The aim of this study was to evaluate the prognostic role of the GGGA haplotype in IDD. METHODS: DNA from 153 sciatica patients who participated in a randomized controlled trial of periradicular infiltration was analysed for IL6 variations rs1800797...

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PMID: 18321738
DOI: 10.1016/j.ejpain.2008.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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