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Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal caliciviruses

4 Mar 2008

Abstract excerpt

The mechanism and role of RNA structure elements in the replication and translation of Caliciviridae remains poorly understood. Several algorithmically independent methods were used to predict secondary structures within the Norovirus, Sapovirus, Vesivirus and Lagovirus genera. All showed profound suppression of synonymous site variability (SSSV) at genomic 5' ends and the start of the sub-genomic (sg)...

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PMID: 18319285
DOI: 10.1093/nar/gkn096

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