Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.

Journal of virology - 1 Mar 2010

Bailey Dalan, Karakasiliotis Ioannis, Vashist Surender, Chung Liliane Man Wah, Rees Jivan, Reese Jivan, McFadden Nora, Benson Alicia, Yarovinsky Felix, Simmonds Peter, Goodfellow Ian

Abstract excerpt

Interactions of host cell factors with RNA sequences and structures in the genomes of positive-strand RNA viruses play various roles in the life cycles of these viruses. Our understanding of the functional RNA elements present in norovirus genomes to date has been limited largely to in vitro analysis. However, we recently used reverse genetics to identify evolutionarily conserved RNA structures and sequences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Norovirus

Share to Nucleic Acid Conformation

Share to Open Reading Frames

Share to Pyrimidines

Share to STAT1 Transcription Factor

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 20053745
DOI: 10.1128/JVI.02053-09
PMCID: PMC2826041

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.PMID 20053745Read ↗

Protruding Domain of Capsid Protein Is Necessary and Sufficient To Determine Murine Norovirus Replication and Pathogenesis <i>In Vivo</i>Semantic proximity Read ↗

Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal calicivirusesSemantic proximity Read ↗

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2Semantic proximity Read ↗

Diverse roles and interactions of RNA structures during the replication of positive-stranded RNA viruses of humans and animalsSemantic proximity Read ↗

Genetic evidence of a long-range RNA-RNA interaction between the genomic 5' untranslated region and the nonstructural protein 1 coding region in murine and bovine coronaviruses.Semantic proximity Read ↗

Gammaherpesvirus ncRNAs share conserved features of binding and virulence despite lack of sequence conservationSemantic proximity Read ↗

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life CycleSemantic proximity Read ↗

The highly conserved stem-loop II motif is dispensable for SARS-CoV-2Semantic proximity Read ↗

High-Resolution X-Ray Structure and Functional Analysis of the Murine Norovirus 1 Capsid Protein Protruding DomainSemantic proximity Read ↗

Characterization of the RNA components of a putative molecular switch in the 3' untranslated region of the murine coronavirus genome.Semantic proximity Read ↗

Norovirus replication and attenuationSemantic proximity Read ↗

Structures and Functions of the 3′ Untranslated Regions of Positive-Sense Single-Stranded RNA Viruses Infecting Humans and AnimalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.