Article
[Polymorphism of human MDR1 gene in the Siberian and central Asian populations].
Molekuliarnaia biologiia - 1 Jan 2000
Pel's Ia R, Marusin A V, Spiridonova M G, Stepanov V A
Abstract excerpt
The multidrug resistance gene (MDR1, ABCB1) encodes transmembrane P-glycoprotein an ATP-dependent transporter, which is involved in elimination of drugs, xenobiotics, peptides from a cell. It is expressed in such organs as a brain, kidneys, a liver, a gastroenteric tract. It is supposed, that this protein may take part in formation of individual resistance to action of adverse factors of an environment, such as...
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