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Article

Abnormal postprandial PYY response in insulin sensitive nondiabetic subjects with a strong family history of type 2 diabetes.

International journal of obesity (2005) - 1 Jun 2008

Viardot A, Heilbronn L K, Herzog H, Gregersen S, Campbell L V

Abstract excerpt

OBJECTIVE: Gut-derived hormone peptide YY (PYY) is low in subjects with obesity and type 2 diabetes (T2D). However, it is unknown whether this is a primary defect or a consequence of metabolic disturbances. In this study, we aimed to assess whether low fasting and postprandial PYY secretion is an early defect, potentially promoting the development of obesity and T2D, and whether it is modified by macronutrient...

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Source

Identifiers

PMID: 18317469
DOI: 10.1038/ijo.2008.24

Genes

PYY
REL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal postprandial PYY response in insulin sensitive nondiabetic subjects with a strong family history of type 2 diabetes.PMID 18317469Read ↗

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Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.Semantic proximity Read ↗

Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.Semantic proximity Read ↗

Investigating PYY3-36 and PYY3-36 analogues in the development of an obesity therapySemantic proximity Read ↗

[Relation between peptide YY 3-36 and dietary induced obesity resistant rats].Semantic proximity Read ↗

Peptide YY (PYY) gene polymorphisms in the 3'-untranslated and proximal promoter regions regulate cellular gene expression and PYY secretion and metabolic syndrome traits in vivo.Semantic proximity Read ↗

Leu7Pro polymorphism of PreproNPY associated with an increased risk for type II diabetes in middle-aged subjects.Semantic proximity Read ↗

SNP analyses of postprandial responses in (an)orexigenic hormones and feelings of hunger reveal long-term physiological adaptations to facilitate homeostasis.Semantic proximity Read ↗

The satiety hormone peptide YY as a regulator of appetite.Semantic proximity Read ↗

Interaction of dietary composition and PYY gene expression in diet-induced obesity in rats.Semantic proximity Read ↗

The Leu7Pro polymorphism of preproNPY is associated with decreased insulin secretion, delayed ghrelin suppression, and increased cardiovascular responsiveness to norepinephrine during oral glucose tolerance test.Semantic proximity Read ↗

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