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Article

Parathyroid tumor development involves deregulation of homeobox genes.

Endocrine-related cancer - 1 Mar 2008

Shen H-C Jennifer, Rosen Jennifer E, Yang Lauren M, Savage Sharon A, Burns A Lee, Mateo Carmen M, Agarwal Sunita K, Chandrasekharappa Settara C, Spiegel Allen M, Collins Francis S, Marx Stephen J, Libutti Steven K

Abstract excerpt

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant syndrome caused by mutations in the MEN1 tumor suppressor gene. Loss of the functional second copy of the MEN1 gene causes individuals to develop multiple endocrine tumors, primarily affecting the parathyroid, pituitary, and panc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Homeobox

Share to Multiple Endocrine Neoplasia Type 1

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Source

Open in PubMed Open full text

Identifiers

PMID: 18310293
DOI: 10.1677/ERC-07-0191
PMCID: PMC3133970

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18310293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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