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Article

Effect of mechanical boundary conditions on orientation of angiogenic microvessels.

Cardiovascular research - 1 May 2008

Krishnan Laxminarayanan, Underwood Clayton J, Maas Steve, Ellis Benjamin J, Kode Tejas C, Hoying James B, Weiss Jeffrey A

Abstract excerpt

AIM: Mechanical forces are important regulators of cell and tissue phenotype. We hypothesized that mechanical loading and boundary conditions would influence neovessel activity during angiogenesis. METHODS AND RESULTS: Using an in vitro model of angiogenesis sprouting and a mechanical loading system, we evaluated the effects of boundary conditions and applied loading. The model consisted of rat microvessel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18310100
DOI: 10.1093/cvr/cvn055
PMCID: PMC2840993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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