Article
SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines.
Nucleic acids research - 1 Apr 2008
Demichelis Francesca, Greulich Heidi, Macoska Jill A, Beroukhim Rameen, Sellers William R, Garraway Levi, Rubin Mark A
Abstract excerpt
Translational research hinges on the ability to make observations in model systems and to implement those findings into clinical applications, such as the development of diagnostic tools or targeted therapeutics. Tumor cell lines are commonly used to model carcinogenesis. The same tumor cell line can be simultaneously studied in multiple research laboratories throughout the world, theoretically generating results...
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