Article
Matrix metalloproteinase-3 genotypes influence recovery from hepatitis B virus infection.
Journal of Korean medical science - 1 Feb 2008
Cheong Jae Youn, Cho Sung Won, Lee Jung A, Lee Kwang Jae, Wang Hee Jung, Lee Jong Eun, Kim Jin Hong
Abstract excerpt
The reasons for the viral persistence of hepatitis B virus (HBV) infection are unknown, but are probably related to host immune factors. Several matrix metalloproteinases (MMPs) can regulate an inflammatory response. The aim of this study was to assess the effects of the single nucleotide polymorphisms (SNPs) of MMP-3 and -9 genes on the susceptibility to persistent HBV infection. We studied 489 Korean patients...
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