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Article

Molecular chaperones and selection against mutations.

Biology direct - 26 Feb 2008

Tomala Katarzyna, Korona Ryszard

Abstract excerpt

BACKGROUND: Molecular chaperones help to restore the native states of proteins after their destabilization by external stress. It has been proposed that another function of chaperones is to maintain the activity of proteins destabilized by mutation, weakening the selection against suboptimal protein variants. This would allow for the accumulation of genetic variation which could then be exposed during...

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Identifiers

PMID: 18298866
DOI: 10.1186/1745-6150-3-5
PMCID: PMC2267774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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