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Article

Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy.

Traffic (Copenhagen, Denmark) - 1 May 2008

Bugnicourt Amandine, Mari Muriel, Reggiori Fulvio, Haguenauer-Tsapis Rosine, Galan Jean-Marc

Abstract excerpt

Proteins carrying EPS15 homology (EH) domains are present from yeast to mammals. The characterized members of this protein family are all involved in intracellular trafficking, typically endocytosis and endocytic recycling. We focused on two members of this family in Saccharomyces cerevisiae Irs4p and Tax4p, whose functions are less well characterized. We show that the deletion of IRS4 altered the function of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18298591
DOI: 10.1111/j.1600-0854.2008.00715.x

Genes

EPS15
IRS4
VPS51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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